Researchers have discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development. This finding ...

Combined epigenetic and immune checkpoint therapy altered the tumour microenvironment in platinum-resistant ovarian cancer.

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Using cannabis may cause changes in the human body's epigenome, a study of over 1,000 adults suggests. The epigenome functions like a set of switches, activating or deactivating genes to change how ...

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary ...

About half of Americans between 45 and 84 have atherosclerosis without knowing it. Diseases linked to atherosclerosis are the leading cause of death in the United States. The condition develops when ...

Discover how emerging epigenetic clock models are reshaping our understanding of ovarian aging and revealing both the promise and current limits of predicting fertility outcomes through biological age ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...