Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University of Connecticut researchers have shown that packaging mRNA like a virus could ...

Better mRNA release inside cells boosts vaccine and gene editing performance, enabled by redesigned lipid molecules that grip ...

A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life reconstructions ever created. Using computer technology, scientists have ...

Right before BioNTech was due to announce its 2025 results, the company’s co‑founders, Ugur Sahin and Özlem Türeci, revealed they would leave the company to focus on developing next‑generation mRNA ...

Researchers shamelessly copy viral strategies to get mRNA medicines into cells in one piece (Illustration courtesy of Joe Luciani ...

Scientists developed a new mRNA platform that keeps vaccines and therapies effective in older adults and patients with obesity, where current treatments often lose potency.

Since the COVID-19 pandemic, mRNA vaccines have gained attention as a next-generation pharmaceutical technology. mRNA therapeutics work by delivering genetic instructions that enable cells to produce ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...